The UK Living Kidney Sharing Scheme (UKLKSS) is a UK-wide kidney exchange programme in which donor-recipient pairs who are incompatible by blood type or human leukocyte antigen (HLA) type can participate to achieve a compatible or better matched transplant with a greater chance of successful outcome.
The UKLKSS includes paired/pooled donation and altruistic donor chains initiated by non-directed altruistic donors.
See the figure below to see how the UKLKSS works.
Incompatible donor-recipient pairs register with UKLKSS.
When two pairs are matched this is called “paired” donation; when more than two pairs is involved, it is called “pooled” donation.
Compatible donor-recipients can register with the scheme to achieve better HLA or age match.
Non-directed Altruistic Donation
Non-directed altruistic donation involves a person volunteering to donate a kidney anonymously to a recipient on the waiting list.
This type of donation can initiate an altruistic donor chain of up to three transplants or is allocated to a recipient with higher priority for transplant.